Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

FBXL8

contributors: - updated : 30-07-2004

HGNC name	F-box and leucine-rich repeat protein 8
HGNC id	17875

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a 40AAs F box motif and several leucine rich repeats (LRR) motifs at the C terminus

HOMOLOGY

Homologene

FAMILY

F box protein family

CATEGORY

adaptor

SUBCELLULAR LOCALIZATION

intracellular

basic FUNCTION	phosphorylation dependent ubiquination
	substrate recognition subunit of SCF ubiquitin protein ligase complex

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

one of the four subunits of the E3 ubiquitin protein ligase complex (SCF) with SKP1,CUL1,RBX1,F boxprotein bringing ubiquitin conjugating enzymes to substrates recruited by F-box

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS