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FLASH GENE
Symbol KCNJ8 contributors: - updated : 24-05-2006
HGNC name potassium inwardly-rectifying channel, subfamily J, member 8
HGNC id 6269
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two membrane-spanning domains and an amphipatic region pore,including the P domain with the K+ channel signature
  • an ATP-binding regulatory domain
    • mono polymer homomer , tetramer
    HOMOLOGY
    Homologene
    FAMILY potassium channel subfamily J
    CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in the regulation of membrane potential
  • potassium non voltage-gated channel, inwardly rectifying
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component constituent with SUR2 of an ATP dependent potassium channel
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS