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FLASH GENE

Symbol

DNAJA4

contributors: mct/npt - updated : 01-09-2008

HGNC name	DnaJ (Hsp40) homolog, subfamily A, member 4
HGNC id	14885

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart       highly Endocrine neuroendocrine pituitary     highly Nervous nerve       highly Reproductive male system prostate     moderately Respiratory respiratory tract trachea     highly Urinary kidney       moderately

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow       Epithelial secretory glandular endocrine   Epithelial secretory glandular exocrine   Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a J domain
	a CR domain

conjugated

LipoP , Other

HOMOLOGY

Homologene

FAMILY

DnaJ protein family

CATEGORY

chaperone/stress

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

SREBF-regulated chaperone involved in the cholesterol biosynthesis pathway

CELLULAR PROCESS

protein, post translation, folding

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

cholesterol biosynthesis pathway

a component

INTERACTION

DNA

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS