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FLASH GENE

Symbol

DEFB126

contributors: mct - updated : 04-05-2021

HGNC name	defensin, beta 126
HGNC id	15900

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to male age infertility

Variant & Polymorphism other	age-related sperm differential methylation that accounted for 64 p100 of the effect of male age on lower fertilization rate
	common mutation in the defensin DEFB126 causes impaired sperm function and subfertility

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS