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FLASH GENE
Symbol CPNE4 contributors: - updated : 10-06-2004
HGNC name copine IV
HGNC id 2317
DNA
TYPE functioning gene
STRUCTURE 500.00 kb     16 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text several transcripts
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Nervousbrain   highly
Reproductivemale systemprostate  highly
 male systemtestis  highly
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two N terminal copies of two C2 (calcium/calmodulin binding) domains
  • a C terminal region distantly to the A domain
  • one WWFA domain
    • HOMOLOGY
    Homologene
    FAMILY copine family
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    text secretory vesicle
    basic FUNCTION
  • calcium-dependent,phospholipid binding protein,potentially involved in regulating membrane trafficking and in protein-protein interactions
  • may have an important role in prostate regulation and development
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text
  • vesicular transport
  • membrane trafficking
    • PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
    phospholipid binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS