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FLASH GENE
Symbol CLSTN3 contributors: - updated : 24-08-2007
HGNC name calsyntenin 3
HGNC id 18371
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a cytoplasmic synaptic Ca2+ binding domain
  • two cadherin domains
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to rattus Cstn3
    ortholog to murine Clstn3
    homolog to Drosophila calsyntenin-1
    homolog to C.elegans B0034.3a
    Homologene
    FAMILY
    CATEGORY adhesion , regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION modulating calcium-mediated postsynaptic signals
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    calcium Ca2+
    protein interacting with APP (coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS