Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CLSTN2 contributors: mct/ - updated : 24-08-2007
HGNC name calsyntenin 2
HGNC id 17448
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a cytoplasmic synaptic Ca2+ binding domain
  • two cadherin domains
    • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Clstn2
    homolog to rattus Cstn2
    homolog to Drosophila calsyntenin-1
    homolog to C.elegans B0034.3a
    Homologene
    FAMILY
    CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • modulating calcium-mediated postsynaptic signals
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
    • protein
  • interacting with APP (coordinated metabolism of alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS