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FLASH GENE
Symbol CLSTN2 contributors: mct/ - updated : 24-08-2007
HGNC name calsyntenin 2
HGNC id 17448
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainforebraincerebral lobetemporal lobemoderately Homo sapiens
 brainforebraincerebral lobetemporal lobemoderately Homo sapiens
Reproductivefemale systembreastmammary gland  
 male systemprostate   
 male systemtestis  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a cytoplasmic synaptic Ca2+ binding domain
  • two cadherin domains
    • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Clstn2
    homolog to rattus Cstn2
    homolog to Drosophila calsyntenin-1
    homolog to C.elegans B0034.3a
    Homologene
    FAMILY
    CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • modulating calcium-mediated postsynaptic signals
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
    • protein
  • interacting with APP (coordinated metabolism of alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS