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FLASH GENE

Symbol

SCGB1A1

contributors: mct - updated : 08-04-2013

HGNC name	secretoglobin, family 1A, member 1 (uteroglobin)
HGNC id	12523

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --other   differentially expressed in infants with infant respiratory distress syndrome (iRDS)

Susceptibility

to asthma (see also IGER)

Variant & Polymorphism

Candidate gene	candidate for the development of a new immunotherapy for lung cancer
Marker
Therapy target

ANIMAL & CELL MODELS

proinflammatory state in mice homozygous for a null allele of the SCGB1A1 gene (SCGB1A1-/-) suggesting a central role for the nonciliated secretory cell in this process