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FLASH GENE

Symbol

FGF9

contributors: mct/npt/pgu - updated : 28-01-2013

HGNC name	fibroblast growth factor 9 (glia-activating factor)
HGNC id	3687

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	spontaneous dominant mouse mutant, Elbow knee synostosis (Eks), shows elbow and knee joint synosostis, and premature fusion of cranial sutures
	loss of Fgf9 in XX Wnt4(-/-) gonads does not rescue their partial female-to-male sex-reversal
	embryos lacking Fgf9 show mesenchymal hypoplasia, decreased epithelial branching and, by the end of gestation, hypoplastic lungs that cannot support life