basic FUNCTION
| acting as an anion transporting ATPase |
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catalysing the extrusion of arsenite |
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representing an integral component of a posttranslational pathway of membrane protein insertion whose targeting is mediated by TRC |
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interacting posttranslationally with tail-anchored proteins in a TMD-dependent manner for delivery to a proteinaceous receptor at the ER membrane |
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acting as a modulator of insulin signaling |
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playing a crucial role in biogenesis of at least one essential tail-anchored protein |
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ASNA1-mediated pathway of membrane insertion of SERP1 and SEC61B may relate to functions of these proteins in the ER stress response |
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cytosolic ATPase that are responsible for two different ATP-dependent pathways of tail-anchored protein biogenesis |
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can mediate membrane insertion of SERP1 and SEC61B without the participation of other cytosolic proteins by a mechanism that depends on the presence of ATP or ADP and a protease-sensitive receptor in the ER membrane |
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role for GET4/UBL4A in recycling ASNA1 from the ER membrane at the end of the targeting reaction |
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cytosolic ATPase with a central role in the post-translational targeting pathway of tail-anchored (TA) proteins to the endoplasmic reticulum (ER) membrane |