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FLASH GENE

Symbol

ARL5A

contributors: - updated : 20-02-2006

HGNC name	ADP-ribosylation factor-like 5A
HGNC id	696

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	six GTP binding motifs
	four conserved motifs critical for guanine nucleotide binding and hydrolysis
	a C-terminal consensus ARF motif

conjugated

LipoP

mono polymer

monomer

HOMOLOGY

interspecies	homolog to Drosophila CG7197
	ortholog to C.elegans Arl5
	homolog to C.elegans B0336.2

Homologene

FAMILY	small GTPase superfamily
	ADP-ribosylation factors (ARF) family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,nucleolus

basic FUNCTION	having a GTPase activity
	may playing a role(s) in nuclear dynamics and/or signaling cascades during embryonic development

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

development

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	nucleotide,
	GTP

protein

binding heterochromatin protein 1 alpha

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS