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FLASH GENE

Symbol

DDB2

contributors: mct - updated : 04-12-2018

HGNC name	damage-specific DNA binding protein 2, 48kDa
HGNC id	2718

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	DDB2–/– mice are susceptible to UV-induced skin carcinogenesis
	mice genetically deficient in Ddb2 exhibited increased susceptibility to colon tumor development in a manner associated with higher abundance of the Wnt receptor-expressing cells and greater activation of the downstream Wnt pathway