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FLASH GENE
Symbol DHRS9 contributors: mct - updated : 01-06-2007
HGNC name dehydrogenase/reductase (SDR family) member 9
HGNC id 16888
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
four motifs conserved in the short chain (SDR) family of proteins
mono polymer homomer , dimer
HOMOLOGY
Homologene
FAMILY SDR family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • critical role in retinal metabolism in airway epithelia as well as in other epithelia of colon, tongue, esophagus
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein expression regulated by APC and CDX2
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in Burkitt lymphoma and in T-cell acute lymphoblastic leukemia
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS