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FLASH GENE
Symbol DHRS9 contributors: mct - updated : 01-06-2007
HGNC name dehydrogenase/reductase (SDR family) member 9
HGNC id 16888
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveintestinesmall intestine  highly
 mouthtongue   
 pharynx   highly
Nervousbrain    
 spinal cord    
Reproductivemale systemtestis   
Respiratorylung    
 respiratory tracttrachea  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connectivebone   
Lymphoid    
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
four motifs conserved in the short chain (SDR) family of proteins
mono polymer homomer , dimer
HOMOLOGY
Homologene
FAMILY SDR family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • critical role in retinal metabolism in airway epithelia as well as in other epithelia of colon, tongue, esophagus
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein expression regulated by APC and CDX2
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in Burkitt lymphoma and in T-cell acute lymphoblastic leukemia
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS