Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --low
|  
|
in ductal carcinomas, decreased levels in primary tumors correlate with local recurrence and death in long-term follow-up of patients ![](pubmed.jpg) | constitutional
|  
|  
|  
|  
|
of either CDH2 or LIN7C disrupts neural tube formation ![](pubmed.jpg) | constitutional
|  
|  
|  
|  
|
loss of CDH2 alters the actin cytoskeleton, leading to a decrease in the cortical actin-binding protein, CTTN, which associates with KCNA5 channel and regulates its function in the heart ![](pubmed.jpg) | tumoral
|  
|  
| --low
|  
|
by promoter methylation in colorectal cancer patients ![](pubmed.jpg) | constitutional
|  
|  
| --over
|  
|
partially attenuated nucleus pulposus (NP) cell senescence, decreased ROS content and inhibited the activation of the NFKB1 pathway under the high glucose condition ![](pubmed.jpg) | |