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FLASH GENE
Symbol WFDC12 contributors: mct - updated : 20-06-2011
HGNC name WAP four-disulfide core domain 12
HGNC id 16115
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide
  • WAP domains playing pivotal roles in the antimicrobial and/or antiprotease activities and their application in therapeutics are expected to have practical value
    • HOMOLOGY
    intraspecies homolog to elafin
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • protease inhibitor
  • antibacterial proteins inhibiting the growth of both Escherichia coli and Staphylococcus aureus
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS