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FLASH GENE

Symbol

LRRC2

contributors: npt - updated : 21-07-2008

HGNC name	leucine-rich repeat-containing 2
HGNC id	14676

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	gene in gene, antisens
text	LUZP3 was localized within the first intron of LRRC2 with an antiparallel transcription orientation
STRUCTURE	64.66 kb     9 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

regionally located

located in C3CER1

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 5108 43 371 - Kiss variant 2 - - 4909 - 371 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol blood / hematopoietic spleen       highly Cardiovascular heart       highly Digestive liver         Endocrine pancreas         Nervous brain         Reproductive male system prostate       Respiratory lung         Urinary kidney       lowly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular endocrine   Epithelial secretory glandular exocrine   Lymphoid         Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	seven leucine-rich repeats
	two putative nuclear localization signals (NLS)

HOMOLOGY

interspecies	homolog to murine Lrrc2
	homolog to Drosophila CG13344

intraspecies

homolog to RSU1

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION

basic FUNCTION

may playing a role in protein-protein interaction

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS