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FLASH GENE

Symbol

C20orf10

contributors: - updated : 20-07-2006

HGNC name	chromosome 20 open reading frame 10
HGNC id	15856

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	20q12-13.12      Physical location : -
Synonym name	TP53-target gene
Synonym symbol(s)	DJ453C12.5, CLG01, TP53TG5

DNA

TYPE	functioning gene
STRUCTURE	4.00 kb     5 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / hematopoietic bone marrow     moderately Connective adipose     predominantly Connective bone     moderately

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

HOMOLOGY

interspecies

homolog to Drosophila cg7187

Homologene

FAMILY

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
text	cell cycle-dependent intracellular localization

basic FUNCTION	involved in the negative regulation of cell growth
	may play a significant role in p53/TP53-mediating signaling pathway

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

p53/TP53-mediating signaling pathway

a component

INTERACTION

DNA

RNA

small molecule

protein

p53/TP53

cell & other

REGULATION

induced by	TP53
		UV-irradation
		hydrogen peroxide treatment
		treatment with a DNA-damaging reagent

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS