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FLASH GENE

Symbol

PPP1R14B

contributors: mct - updated : 10-07-2014

HGNC name	protein phosphatase 1, regulatory (inhibitor) subunit 14B
HGNC id	9057

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

conjugated

PhosphoP

HOMOLOGY

Homologene

FAMILY

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm
	intracellular,nucleus

basic FUNCTION	participating in regulatory events at the trailing edge of migrating cells and modulating retraction of endothelial and epithelial cells
	myosin phosphatase (MP) inhibitory subunit

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

inhibitor of PPP1CA

cell & other

REGULATION

activated by

phosphorylation by PKC on THr57 and a ser

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS