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FLASH GENE
Symbol PPP1R14B contributors: mct - updated : 10-07-2014
HGNC name protein phosphatase 1, regulatory (inhibitor) subunit 14B
HGNC id 9057
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Endocrineneuroendocrinepituitary  highly
Lymphoid/Immunelymph node   highly
Respiratorylung   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated PhosphoP
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus
basic FUNCTION
  • participating in regulatory events at the trailing edge of migrating cells and modulating retraction of endothelial and epithelial cells
  • myosin phosphatase (MP) inhibitory subunit
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein inhibitor of PPP1CA
    cell & other
    REGULATION
    activated by phosphorylation by PKC on THr57 and a ser
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS