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FLASH GENE
Symbol ASB5 contributors: np - updated : 08/09/2003
HGNC name ankyrin repeat and SOCS box-containing 5
HGNC id 17180
Location 4q34.2      Physical location : 177.134.827 - 177.190.373
Synonym name SOCS box protein ASB-5
DNA
TYPE functioning gene
STRUCTURE 55.55 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text multiple alternatively spliced transcripts
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 - 3042 36.2 329 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six N terminal ankyrin (ANK) repeats
  • a conserved one C-terminal SOCS box motif
  • HOMOLOGY
    interspecies homolog to murine Asb5
    homolog to Drosophila lk6
    homolog to C.elegans r166.5
    Homologene
    FAMILY
  • ankyrin repeat and SOCS box-containing (ASB) family of proteins
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    CELLULAR PROCESS protein, post translation, targeting
    protein, degradation
    protein, ubiquitin dependent proteolysis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    intracellular signaling cascade
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • JAK kinases
  • activated cytokine receptors
  • cell & other
    REGULATION
    induced by cytokines
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS