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FLASH GENE

Symbol

SLC15A3

contributors: np/ - updated : 14-04-2010

HGNC name	solute carrier family 15, member 3
HGNC id	18068

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	14.70 kb     8 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_016582 8 - 2134 NP_057666 - 581 - 2001 11336635

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart       lowly Homo sapiens Lymphoid/Immune spleen       highly Homo sapiens Reproductive female system placenta     highly Homo sapiens Respiratory lung       highly Homo sapiens

cells

System Cell Pubmed Species Stage Rna symbol Blood/Hematopoietic leukocyte Homo sapiens

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		fibrous
STRUCTURE

motifs/domains

HOMOLOGY

interspecies

homolog to murine C.AMP inducible gene 1

intraspecies

homolog to PHT1

Homologene

FAMILY

PTR2/POT transporter family

CATEGORY

transport

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

involved in the protein catabolic pathway in the lymphatic system

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   by hypermethylation in head and neck tumors

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS