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FLASH GENE
Symbol SLC15A3 contributors: np/ - updated : 14-04-2010
HGNC name solute carrier family 15, member 3
HGNC id 18068
Location 11q12.2      Physical location : 60.704.554 - 60.719.257
Synonym name
  • likely ortholog of rat
  • peptide/histidine transporter 2
  • peptide transporter 3
  • osteoclast transporter
    • Synonym symbol(s) PHT2, PTR3, FLJ26631, OCTP
    DNA
    TYPE functioning gene
    STRUCTURE 14.70 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 2134 - 581 - 2001 11336635
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   lowly Homo sapiens
    Lymphoid/Immunespleen   highly Homo sapiens
    Reproductivefemale systemplacenta  highly Homo sapiens
    Respiratorylung   highly Homo sapiens
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticleukocyte Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES fibrous
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine C.AMP inducible gene 1
    intraspecies homolog to PHT1
    Homologene
    FAMILY
  • PTR2/POT transporter family
    • CATEGORY transport
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in the protein catabolic pathway in the lymphatic system
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    by hypermethylation in head and neck tumors
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS