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FLASH GENE
Symbol CHODL contributors: mct/npt - updated : 30-03-2009
HGNC name chondrolectin
HGNC id 17807
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 2625 28.3 273 - Clark (2003), Weng (2003)
- - - - - is localized in the ER-Golgi apparatus Weng (2003), Claessens (2007)
  • transmembrane protein, differentially expressed in T lymphocytes
  • - - - - - . localizes in the late endoplasmic reticulum . differentially expressed in thymocytes and lymphocytes suggesting an important biological function during T cell development Weng (2003), Claessens (2007)
    devoid of the transmembrane domain and terminate in QDEL, an ER retention signal
    - - - - - . localizes in the late endoplasmic reticulum . differentially expressed in thymocytes and lymphocytes suggesting an important biological function during T cell development. Weng (2003), Claessens (2007)
    devoid of the transmembrane domain and terminate in QDEL, an ER retention signal
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticspleen   lowly
    Digestiveintestinesmall intestinejejunumcrypt of Lieberkuhn 
    Nervousbrain    
    Reproductivemale systemtestis  highly
    Respiratorylung    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularexocrine 
    Lymphoid    
    Muscularsmooth   
    Muscularstriatumcardiac  
    Muscularstriatumskeletal  
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Musculardifferentiated cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text kidney, spleen, muscle, heart, liver
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • an N-terminal signal peptide with a putative cleavage site, and one CRD domain
  • a long extracellular domain containing an isolated C-type CRD motif
  • a single membrane-spanning domain near the C terminus
  • a short cytoplasmic tail
  • mono polymer monomer
    HOMOLOGY
    interspecies ortholog to murine Chodl
    intraspecies homolog to LAYL
    Homologene
    FAMILY
  • chondrolectin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,nuclear envelope,ext
    text type 1a transmembrane protein
    basic FUNCTION
  • having sugar binding activity
  • may be playing an important biological function during T cell development (Claessens 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interaction with RABGGTB (Claessens 2008)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS