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FLASH GENE

Symbol

FUT3

contributors: mct/ - updated : 11-06-2020

HGNC name	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
HGNC id	4014

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

LE

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --other   altered expression of fucosylation pathway gene(FUT3), correlated with poor survival in patients with non&8209;small cell lung cancer (NSCLC)

Susceptibility

to intestinal-type gastric cancer

Variant & Polymorphism other	variants (and haplotypes) in FUT2 (Se), FUT3 (Le) and FUT6 associated with intestinal-type gastric cancer

Candidate gene
Marker	could be useful to predict respectively breast cancer susceptibility
	is a predictive factor for poor overall survival and recurrence free survival in patients with Clear Cell Renal Cell Carcinoma
Therapy target

ANIMAL & CELL MODELS