Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

MAP3K11

contributors: mct/ - updated : 20-05-2016

HGNC name	mitogen-activated protein kinase kinase kinase 11
HGNC id	6850

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral somatic mutation       in MSI gastrointestinal carcinomas tumoral     --over   in breast cancer cells

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     therapeutics that target MAP3K11 or PIN1 could prove beneficial for a subset of cancers where the MAP3K11-PIN1 pathway is dysregulated cancer reproductive breast may be an important therapeutic target for the treatment of invasive breast cancer

ANIMAL & CELL MODELS