Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

ADAMTS14

contributors: npt/ - updated : 06-02-2006

HGNC name	ADAM metallopeptidase with thrombospondin type 1 motif, 14
HGNC id	14899

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain       lowly Respiratory lung       lowly Visual eye

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

fetal, pregnancy

Text	lung and kidney, placenta (lowly)

PROTEIN

PHYSICAL PROPERTIES		Amphiphilic
STRUCTURE

motifs/domains	a propeptide region
	a metalloproteinase domain
	a disintegrin-like domain
	a cysteine-rich domain
	a thrombospondin type 1 (TS) motif

conjugated

MetalloP

HOMOLOGY

interspecies	homolog to Drosophila kst
	homolog to murine Adamts 14
	homolog to C.elegans sma-1

intraspecies	homolog to ADAMTS3
	homolog to ADAMTS2

Homologene

FAMILY

ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family

CATEGORY

adhesion , enzyme

SUBCELLULAR LOCALIZATION	extracellular
text	associated with the extracellular matrix

basic FUNCTION	having aminoprocollagen activity
	active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia

CELLULAR PROCESS

protein, degradation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS