Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ADAMTS15 contributors: npt/ - updated : 26-09-2002
HGNC name ADAM metallopeptidase with thrombospondin type 1 motif, 15
HGNC id 16305
Location 11q25      Physical location : 130.318.868 - 130.346.539
Synonym name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15
  • metalloprotease disintegrin 15 with thrombospondin domains
    • Synonym symbol(s) MGC126403, ADAM-TS15
    EC.number EC 3.4.24.-
    DNA
    TYPE functioning gene
    STRUCTURE 24.85 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 2853 103 950 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialabsorptive excretory   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • ADAM cystein-rich domain
  • thrombospondin type 1 domain
    • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to C.elegans R10H10.1
    Homologene
    FAMILY
  • ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family
  • reprolysin family zinc metalloprotease
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in intestinal epithelial cells wound-healing processes and may have important pathophysiological roles in intestinal cells
    • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS