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FLASH GENE
Symbol BIRC3 contributors: mct/pgu - updated : 05-05-2015
HGNC name baculoviral IAP repeat-containing 3
HGNC id 591
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral fusion      
rearranged with MALT1 :t(11;18)(q21;q21) in marginal zone cell lymphoma
tumoral     --over  
in lung cancer and malignant pleural mesothelioma and promoting tumor cell survival
tumoral     --other  
is a common mechanism across marginal zone B-cell lymphomagenesis
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
therapeutic opportunities in the treatment of cancer
ANIMAL & CELL MODELS