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FLASH GENE
Symbol ESAM contributors: mct - updated : 10-05-2023
HGNC name endothelial cell adhesion molecule
HGNC id 17474
ASSOCIATED DISORDERS
corresponding disease(s) DDIDE
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in some primary acute myeloid leukemia cells
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • is a useful marker for studying both human hematopoietic stem cells and leukemia cells
  • candidate circulating biomarker to predict the risk of progression to kidney failure
  • Therapy target
    ANIMAL & CELL MODELS
  • mice with endothelial cell-selective adhesion molecule deficiency develop coronary microvascular rarefaction and left ventricle diastolic dysfunction