| basic FUNCTION
| endogenous stabilizer of microtubule cytoskeleton EGF protection and of intestinal barrier function against oxidative injury |
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acting as a serine-threonine kinase |
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mediating insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes |
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serving as the receptor for phorbol esters, a class of tumor promoters |
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playing a central role in epithelial cell polarization |
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involved in the control of pre-mRNA splicing and partcularly controling DNA topoisomerase-dependent |
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plays an important role in supporting cell survival  |
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may function as a physiological BAX kinase to directly phosphorylate and interact with BAX, leading to sequestration of BAX in cytoplasm and abrogation of the proapoptotic function of BAX |
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caspase-2 pre-mRNA splicing |
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regulator of cardiomyocyte myofilament protein phosphorylation |
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might play an important role during the cardiac hypertrophic process |
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regulates epidermal growth factor-induced chemotaxis of breast cancer cells |
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required for macrophage migration and is required for CSF1-induced chemotaxis of macrophages |
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expression of PRKCZ and PRKCI or both are dispensable for primitive and adult hematopoietic stem cell fate determination in steady-state and stress hematopoiesis |
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NTRK2 and PRKCZ, two critical regulators of synaptic plasticity, facilitate DLG4 targeting to synapses |
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is a critical metabolic tumor suppressor in cancer (PMId: 23374352) |
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acts as a metabolic tumor suppressor by inhibiting PHGDH expression and activity |
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direct or indirect role for PRKCZ in the biochemical response to nutrient stress activated by the lack of glucose in cells that require this nutrient for survival and growth |
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is a critical player in the important metabolic pathway for cancer |
