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FLASH GENE

Symbol

XKR6

contributors: mct/npt - updated : 03-09-2009

HGNC name	XK, Kell blood group complex subunit-related family, member 6
HGNC id	27806

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_173683 3 - 3761 NP_775954 71 641 - Appel (2002)

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine small intestine

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial barrier/lining

cells

System Cell Pubmed Species Stage Rna symbol Skin/Tegument keratinocyte

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

homolog to C.elegans F21A10.1

Homologene

FAMILY	PDZ conserved binding motif-containing proteins family
	XK family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

implicated in regulating the timing of apoptosis (Harley 2009)

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to systemic lupus erythematosus (SLE)

Variant & Polymorphism other	polymorphisms implicated in SLE risk (Harley 2009)

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS