Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | AMHR2 | contributors: - updated : 10-05-2006 |
HGNC name | anti-Mullerian hormone receptor, type II |
HGNC id | 465 |
|
Corresponding disease |
| ||
Location | 12q13 Physical location : 53.817.638 - 53.825.318 | ||
Synonym name | Mullerian inhibiting substance type II receptor | ||
Synonym symbol(s) | AMHR , AMH2, MISR2 |
DNA |
TYPE | functioning gene |
STRUCTURE | 7.00 kb 11 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
---|
EXPRESSION |
Type | restricted |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
Homologene |
FAMILY | ser/thr family of protein kinases, TGFB receptor subfamily |
CATEGORY | receptor |
SUBCELLULAR LOCALIZATION | plasma membrane |
basic FUNCTION | receptor for anti-mullerian hormone, activating SMAD transcriptional regulators |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, |
magnesium or manganese |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | PMDS2 |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |