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FLASH GENE

Symbol

FKBP9

contributors: mct/npt - updated : 24/12/2008

HGNC name	FK506 binding protein 9, 63 kDa
HGNC id	3725

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	49.50 kb     10 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 10 - 3491 isoform 1 63 570 - Patterson (2002)

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart       highly Digestive liver       moderately Respiratory lung       highly Urinary kidney       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	multiple N terminal FK506 binding
	peptidyl prolyl cis-trans isomerase (rotamase) domains
	a C terminal tetratricopeptide repeat domain
	EF-hand domain

HOMOLOGY

interspecies

homolog to murine Fkbp9

intraspecies

homolog to FKBP10

Homologene

FAMILY

peptidylprolyl isomerase family

CATEGORY

chaperone/stress , enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,lumen
	intracellular,cytoplasm,organelle,endoplasmic reticulum

basic FUNCTION

accelerate effectively the isomerization of the peptidyl-prolyl bond

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS