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FLASH GENE
Symbol ST8SIA5 contributors: - updated : 22-04-2006
HGNC name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
HGNC id 17827
DNA
TYPE functioning gene
STRUCTURE 77.00 kb     7 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2500 43.8 376 - Kim
- - 1100 - - brain and fetal brain Kim
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland   highly
 thyroid    
Nervousbrain    
Respiratorylung    
Urinarykidney    
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY glycosyltransferase family 29
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,Golgi
text
  • type II membrane protein
  • Golgi (potential)
  • basic FUNCTION involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3
    CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    text glycosylation
    PATHWAY
    metabolism carbohydrate
    signaling
    glycosphingolipid biosynthesis
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS