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FLASH GENE
Symbol C1QTNF6 contributors: mct - updated : 08-03-2010
HGNC name C1q and tumor necrosis factor related protein 6
HGNC id 14343
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one C1q domain
  • one collagen-like domain
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • C1q/TNF family
    • CATEGORY immunity/defense , regulatory
    SUBCELLULAR LOCALIZATION extracellular
    text secreted
    basic FUNCTION
  • circulate in the blood and is potential endocrine hormone
  • mediates the phosphorylation and activation of the 5'-AMP-activated protein kinase in skeletal muscle cells
  • inducing the phosphorylation of acetyl coenzyme A carboxylase and fatty acid oxydation in myocytes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text immune response
    PATHWAY
    metabolism
    signaling signal transduction
    fatty acid metabolism via the AMPK-ACC pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS