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FLASH GENE
Symbol C1QTNF6 contributors: mct - updated : 08-03-2010
HGNC name C1q and tumor necrosis factor related protein 6
HGNC id 14343
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Reproductivefemale systemplacenta  predominantly Homo sapiens
Visualeye   predominantly Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one C1q domain
  • one collagen-like domain
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • C1q/TNF family
  • CATEGORY immunity/defense , regulatory
    SUBCELLULAR LOCALIZATION extracellular
    text secreted
    basic FUNCTION
  • circulate in the blood and is potential endocrine hormone
  • mediates the phosphorylation and activation of the 5'-AMP-activated protein kinase in skeletal muscle cells
  • inducing the phosphorylation of acetyl coenzyme A carboxylase and fatty acid oxydation in myocytes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text immune response
    PATHWAY
    metabolism
    signaling signal transduction
    fatty acid metabolism via the AMPK-ACC pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS