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FLASH GENE
Symbol BRI3 contributors: - updated : 29-08-2005
HGNC name brain protein I3
HGNC id 1109
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • putative transmembrane domain
  • polyadenylation signal
  • N-linked glycosylation site
    • HOMOLOGY
    interspecies homolog to murine Bri3
    intraspecies homolog to BRI2
    Homologene
    FAMILY BRI gene family
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,lysosome
    basic FUNCTION
  • playing an important role in TNF-induced cell death
    • CELLULAR PROCESS cell life, cell death/apoptosis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS