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FLASH GENE
Symbol DNAJC30 contributors: mct/npt - updated : 22-06-2022
HGNC name DnaJ (Hsp40) homolog, subfamily C, member 30
HGNC id 16410
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Cardiovascularheart   highly
Digestivestomach    
Endocrineparathyroid   highly
Hearing/Equilibriumear   highly
Nervousbrain    
Reproductivemale systemtestis   
Respiratoryrespiratory tractlarynx  highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text placenta, brain, liver, kidney, heart, lung
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a DNAJ domain
  • a putative C-terminal transmembrane segment
    • HOMOLOGY
    interspecies homolog to murine Wbscr18
    homolog to C.elegans R10h10.1
    Homologene
    FAMILY
  • DNAJ molecular chaperone homology domain-containing protein family
    • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION
  • is an auxiliary component of ATP-synthase machinery
  • is a protein chaperone required for exchange of damaged complex I subunits
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with mitochondrial ATP-synthase machinery
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) WBS , LHONAR
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS