Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PELI1

contributors: mct/npt/pgu - updated : 15-12-2017

HGNC name	pellino E3 ubiquitin protein ligase 1
HGNC id	8827

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function deficiency of Pellino 1 (PELI1), an E3 ubiquitin ligase, blocked necroptosis

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cardiovascular aquired heart failure target for treatment of cardiac fibrosis and heart failure

ANIMAL & CELL MODELS