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FLASH GENE

Symbol

PRSS22

contributors: - updated : 22-12-2003

HGNC name	protease, serine, 22
HGNC id	14368

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	16p13.3      Physical location : 2.902.727 - 2.908.171
Synonym name	tryptase epsilon
	brain-specific serine protease 4
	protease, serine S1 family member 22
	serine protease 26
Synonym symbol(s)	BSSP-4, MGC9599, SP001LA, UNQ302/PRO343
EC.number	3.4.21.-

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
text	part of a cluster of serine protease genes
STRUCTURE	5.00 kb     6 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine pancreas         Nervous brain

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular endocrine

cells

System Cell Pubmed Species Stage Rna symbol respiratory larynx respiratory lung respiratory trachea

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

fetal

Text	lung highly

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a peptidase S1 domain

HOMOLOGY

interspecies	homolog to Drosophila cg8170
	homolog to C.elegans c07g1.1

Homologene

FAMILY

peptidase family S1

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION

may be involved in proteolysis and peptidolysis

CELLULAR PROCESS

protein, degradation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

Other

developmentally regulated (repressed by time)

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS