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FLASH GENE
Symbol ST3GAL6 contributors: - updated : 08-09-2005
HGNC name ST3 beta-galactoside alpha-2,3-sialyltransferase
HGNC id 18080
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an N-terminal type II transmembrane domain
  • two sialyl motifs
  • a C-terminal motif
  • a large catalytic domain with 297 amino acids
    • HOMOLOGY
    interspecies ortholog to murine Siat 10
    intraspecies homolog to ST3Gal III
    homolog to ST3Gal IV
    homolog to ST3Gal V
    Homologene
    FAMILY glycosyltransferase family 29
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • type II membrane protein
    • basic FUNCTION
  • playing a role in synthesis of sialyl-paragloboside (precursor of sialyl-Lewis X determinant)
  • lipid and protein modification
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism other
    signaling
    aminosugar metabolism and glycolipid metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS