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FLASH GENE

Symbol

JAM3

contributors: shn/npt/pgu - updated : 24-08-2020

HGNC name	junctional adhesion molecule 3
HGNC id	15532

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	JAM-C gene knocked out mice exhibited loss of integrity of the myelin sheath, defective nerve conduction and motor abnormalities
	JAM3 knockdown caused a delay in the hfRPE cell polarization, and JAM3 inhibition significantly decreased the chemokine-induced transmigration of granulocytes through the hfRPE monolayer