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FLASH GENE
Symbol PDK3 contributors: npt/ - updated : 05-05-2006
HGNC name pyruvate dehydrogenase kinase, isoenzyme 3
HGNC id 8811
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • histidine-kinase domain
    • HOMOLOGY
    Homologene
    FAMILY
  • PDK/BCKDK protein kinase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • with PDK2 and PDK4 are primary PPARbeta/delta target genes underlining the importance of the receptor in the control of metabolism (Degenhardt 2007)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS