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FLASH GENE

Symbol

SPG21

contributors: mct/shn - updated : 03-08-2010

HGNC name	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
HGNC id	20373

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

SPG21-/- knockout mice are normal at birth, within several months they develop gradually progressive hind limb dysfunction and display alterations in axon branching in cultured cerebral cortical neurons (Soderblom et al, 2010)