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FLASH GENE
Symbol GTF2A2 contributors: npt/ - updated : 23-02-2004
HGNC name general transcription factor IIA, 2, 12kDa
HGNC id 4647
Location 15q21.2      Physical location : 59.930.262 - 59.949.737
Synonym name
  • general transcription factor IIA, 2 (12kD subunit)
  • transcription initiation factor IIA gamma chain
  • TFIIA p12 subunit
  • weakly similar to W02D9.2 [C.elegans]
  • Synonym symbol(s) TFIIA, HsT18745, TFIIAS, TFIIA-12, TFIIA-gamma, TF2A2
    DNA
    TYPE functioning gene
    STRUCTURE 18.63 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 736 12.5 109 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer heteromer , trimer
    HOMOLOGY
    interspecies homolog to murine Gtf2a2
    homolog to C.elegans Y111b2a.13
    Homologene
    FAMILY
  • TFIIA subunit 2 family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • playing an important role in transcriptional activation
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterotrimer of an alpha (p35), a beta (p19) and a gamma (p12)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TBP (TATA-binding protein)
  • TAF (TBP-associating factor)
  • ZTA (transcriptional activator)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS