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FLASH GENE
Symbol GTF2H3 contributors: npt/ - updated : 19-07-2006
HGNC name general transcription factor IIH, polypeptide 3, 34kDa
HGNC id 4657
Location 12q24.31      Physical location : 124.118.380 - 124.145.334
Synonym name
  • general transcription factor IIH, polypeptide 3 (34kD subunit)
  • basic transcription factor 2 34 kDa subunit
  • TFIIH basal transcription factor complex p34 subunit
  • Synonym symbol(s) BTF2, TFIIH, BTF2-p34, TFB4
    DNA
    TYPE functioning gene
    STRUCTURE 26.95 kb     13 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    13 - 1505 34.4 308 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a C4 type zinc finger
  • HOMOLOGY
    interspecies homolog to yeast S.cerevisiae Ssl1
    Homologene
    FAMILY
  • TFB4 family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in UV resistance
  • CELLULAR PROCESS nucleotide, repair, nucleotide excision repair
    nucleotide, transcription, initiation
    nucleotide, transcription, regulation
    protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • subunit of RNA polymerase II polymerase II transcription initiation factor IIM
  • component of the core TFIIM basal transcritpion factor (one of the six subunits)
  • INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
  • CAK
  • XPB
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS