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FLASH GENE
Symbol STEAP1 contributors: mct - updated : 04-06-2015
HGNC name six transmembrane epithelial antigen of the prostate 1
HGNC id 11378
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral       gain of function
in prostate, bladder, colon, ovarian cancer, Ewing sarcoma
tumoral     --over  
in several types of human cancers, namely prostate, bladder, colon, pancreas, ovary, testis, breast, cervix, and Ewing sarcoma
tumoral     --over  
associated with poor overall survival in colorectal cancer, diffuse large B cell lymphoma, acute myeloid leukemia and multiple myeloma
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
is a potential therapeutic target for T-cell based immunotherapy or antibody therapy in a large panel of cancers
ANIMAL & CELL MODELS