Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

CNKSR2

contributors: - updated : 13-04-2006

HGNC name	connector enhancer of kinase suppressor of Ras 2
HGNC id	19701

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	277.00 kb     22 Exon(s)

MAPPING

cloned

Y

linked

N

status

Map	pter - PHKA2 - DXS8004 - DXS3424 - DXS8005 - DXS8176 - EIF1AX - RPS6KA3 - DXS8267 - DXS8268 - DXS1229 - DXS1528 - DXS8266 - DXS8007 - DXS1390 - DXS8008 - CNKSR2 - DXS7293 - DXS8250 - DXS365 - cen
Authors	Zhang (02)

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain       moderately   brain hindbrain cerebellum   moderately   brain basal nuclei caudate nucleus   moderately   brain diencephalon hypothalamus   moderately   brain diencephalon amygdala   moderately

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	PH domain
	STAR (sterile alpha motif) domain
	PDZ domain

HOMOLOGY

interspecies	homolog to Drosophila kinase suppressor of RAS
	homolog to rattus Maguin 1,membrane associated GUK interacting protein

Homologene

FAMILY

CATEGORY

signaling

SUBCELLULAR LOCALIZATION	plasma membrane,junction
text	cell junction

basic FUNCTION

regulator of signaling

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

signal transduction

RAS/MAPK signaling pathway

a component

INTERACTION

DNA

RNA

small molecule

protein

interacting and targeting with RAF to specific subcellular compartments upon RAS activation

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS